Charles Johnson

Charlie Johnson

Senior Toxicologist

UKRT/ERT

Charlie joined the bibra team in mid-2015 after he completed his MChem degree, which included a six-month organic chemistry project in Queensland, Australia. He is now a senior toxicologist and manages a range of projects, notably for clients within the medical device, pharmaceutical and e-cigarette industries. He has a wealth of experience in the medical device sector. He has conducted biological evaluations for a variety of interesting devices with numerous medical applications, and routinely provides scientific advice to clients with a consideration of biocompatibility testing strategy. He actively keeps up to date with scientific and regulatory advances in the industry, notably with respect to the development of ISO 10993 standards.

Charlie has also been involved in projects assessing safety of e-cigarettes and e-liquids, often in the context of the EU Tobacco Products Directive (TPD) and US FDA Premarket Tobacco Product Application (PMTA) frameworks. He has also co-authored a poster (along with Richard Young) on "Application of the Human Health Risk Assessment Process for Evaluation Electronic Cigarettes" - click here to download.

Charlie’s interest in science is not limited to toxicology, but also extends to the world of beer and brewing. After moving out of London and into rural Kent, he is now an active homebrewer, and is always keen to discuss the amber nectar (with anybody that will listen)!

Charlie's case studies and blog posts

Save yourself the pain of last-minute reformulation with early ingredient screening

Blog articles

Developing a new consumer product? Maybe you’ve come up with the hottest new gadget or e-liquid flavour and are eager to get the product out to market as soon as possible. Prior to mass production, a safety evaluation is key. A preliminary screening assessment of the component ingredients during early development could save you a lot of time and money further down the line.

Evaluating the health risks posed by extractables and leachables from an ENDS device

Case study

In order to market their latest product in the United States, the client was intending to submit a Premarket Tobacco Product Application (PMTA) for a pod-based ENDS device.

FDA memoranda: shedding light on health risk assessment of ENDS in PMTA submissions

Blog articles

In 2016, the United States (US) Food and Drug Administration (FDA) ruled that Electronic Nicotine Delivery Systems (ENDS) were to be regulated just like more traditional tobacco products, meaning that ENDS (e-cigarettes and e-liquids) are subject to premarket review requirements, despite containing no tobacco. ENDS manufacturers must therefore submit a Premarket Tobacco Product Application (PMTA) to the FDA Center for Tobacco Products (CTP) in order to have any chance of legally marketing their products in the US.

Want to read more case studies and blog posts that Charlie has been involved in? Click below to read more.

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